Please note that this is a forum for statisticians and mathematicians to critically evaluate the design and statistical methods used in studies. The subjects (products, procedures, treatments, etc.) of the studies being evaluated are neither endorsed nor rejected by Sense About Science USA. We encourage readers to use these articles as a starting point to discuss better study design and statistical analysis. While we strive for factual accuracy in these posts, they should not be considered journalistic works, but rather pieces of academic writing.
Of the 13,327 registered trials completed between January 1, 2008 and August 31, 2012 that likely fell under the FDAAA reporting requirements, the results of 62 percent were missing as of August 31, 2012.read more
Jennifer Miller, Ph.D., a bioethicist at New York University came up with a way to evaluate the transparency of pharmaceutical companies. She calls it the Good Pharma Scorecard.read more
Prabhat Jha of St. Michael’s Hospital Center for Global Health Research in Toronto on the need for global disease surveillance systems — similar in scope to those that monitor movements in the world of finance.read more
Today the American Medical Association (AMA) joins more than 641 patient advocacy groups, professional societies, medical organizations and thousands of patients worldwide in supporting the global campaign for clinical trial registration and reporting led by AllTrials.read more
This project started out with an email from a journalist. She was frustrated with the number of times she had dealt with scientists who, “demand to see drafts and place conditions on interviews retroactively.” She wanted to know if there was a blog or a how-to list...read more
How a clinical trial is run, how its data is shared, and what post-trial responsibilities the sponsors have to clinical trial participants varies depending on the country, industry and therapeutic area of that trial (among other things). These are the issues discussed at regular brainstorming sessions hosted by the Multi-Regional Clinical Trials (MRCT) Center.read more
There are some bizarre and improbable correlations that show two unlikely variables have a positive relationship. How do scientists then know when a relationship they find in the laboratory is factual?read more
Sense About Science USA would like to wish you and yours a happy, healthy holiday and new year. It’s been a productive first year here at SAS USA–thank you to all our generous supporters. Here’s what we’ve been up to…read more
In this guest piece, Matthew Herder of Dalhousie University in Nova Scotia, Canada shares a template letter that physicians, researchers, civil society groups, investigative journalists and others can use to gain access to unpublished pharmaceutical safety and effectiveness data.read more
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