Please note that this is a forum for statisticians and mathematicians to critically evaluate the design and statistical methods used in studies. The subjects (products, procedures, treatments, etc.) of the studies being evaluated are neither endorsed nor rejected by Sense About Science USA. We encourage readers to use these articles as a starting point to discuss better study design and statistical analysis. While we strive for factual accuracy in these posts, they should not be considered journalistic works, but rather pieces of academic writing.
The controversy over clinical trial transparency exploded last week as the BMJ published a reanalysis of previously hidden data on an antidepressant drug called Paroxetine (or Paxil).read more
Almost half of all the clinical trials ever conducted have never been reported. This is the story of the campaign to find them—and to fix medicine. This is the story of AllTrials.read more
From The Economist: The evidence base for new medications is flawed. Time to fix it.read more
From the Financial Times: Dozens of big investors have backed a campaign by British activists for more transparency in the pharmaceuticals industry.read more
From WSJ’s Pharmalot: In an unprecedented move, a group of 85 asset managers and pension funds is teaming with a U.K. non-profit campaign to pressure drug makers to disclose clinical trial data.read more
In a further sign of an epochal change in medical research, the World Health Organization has renewed its call for researchers to report all the results from clinical trial research.read more
It was once the case, said George Mason University’s Giorgio Ascoli, that people thought gene discovery would rapidly lead to the patenting of genes. “Now,” he said, “you can’t publish if your data isn’t in a gene bank.”read more
The Institute of Medicine report on data sharing makes the campaign for clinical trial transparency unstoppable.read more
Financial Times article announces debut of AllTrialsUS.read more
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